I wish to thank Dr. Matt Thomas of
http://www.dnaprint.com for a very informative
discussion about the DNAPrint results. |
The BGA test determines the probable fractions of
one's ancestry that are Indo-European (European, Middle Eastern and South
Asian), Native American (South and North American), sub-Saharan African (all
African countries but Algeria, Chad, Egypt, Morocco, Sudan and Tunisia) and
East Asian (Japanese, Chinese, Korean and South Pacific). |
Here is a way to interpret the probabilities that one
gets for the different BioGeographical Ancestries (n=ancestral generation):
- (n=1): Suppose one has one
parent that is 100% BGA #1 and one that is 100% BGA #2: Then he/she is
50% BGA1 and 50% BGA2. (One side of his/her
two chromosome strands is BGA1 and the other side is BGA2. In the process of
producing progeny the two strands of the chromosome will equally mix up so that
each strand of the chromosome is 50% BGA1 and 50% BGA2.)
- (n=2): Suppose one has
three grandparents that are 100%
BGA1 and one that is 100% BGA2: Then he/she is 75% BGA1 and 25% BGA2. (One side of his/her two chromosome
strands is BGA1 and the other side is 50% BGA1 and 50% BGA2. In the process of
producing progeny he/she will equally mix up the two strands of the chromosome,
so that there are various possible combinations of BGA1 and BGA2 genes in each
strand of a chromosome, with the most probable combination being 25% BGA2 in
one strand and 25% BGA2 in the other strand. This introduces some uncertainty
in the amount of BGA2 his/her progeny will have, but the uncertainty is very
small for the approximately
60,000 human genes.)
- (n=3): Suppose one has
seven great-grandparents that are
100% BGA1 and one great-grandparent that is 100% BGA2: Then he/she is 87.5%
BGA1 and 12.5% BGA2 to a high degree of
certainty, but he/she could have smaller than 12.5% BGA2.
- (n=4): Suppose one has
fifteen great-great-grandparents
that are 100% BGA1 and one that is 100% BGA2: Then he/she is 93.75%% BGA1 and
6.25% BGA2.
- (n=5): Suppose one has
thirty-one
great-great-great-grandparents that are 100% BGA1 and one that is 100%
BGA2: Then he/she is 96.875% BGA1 and 3.125% BGA2.
- (n=6): Suppose one has
sixty-three
great-great-great-great-grandparents that are 100% BGA1 and one that is
100% BGA2: Then he/she is 98.4375% BGA1 and 1.5625% BGA2.
The analysis above assumes that the BGA2 comes from only one
nearest 100%-BGA2 ancestor; it could come from more than one 100%-BGA2 nearest
ancestor. In that case the ancestors would be further back in time than the
analysis above indicates. Since the errors on the BGA results are usually of
the order of ±2.5% [e.g., for my result given below, my East-Asian value
is (17±2.5)%], one cannot determine fractional ancestry with BGA back
further than great-great-great-grandparents or back no further than 5
generations. For my case of (17±2.5)% East Asian, BGA indicates that
my 100%-East-Asian ancestor was a great-grandparent; it could be that there are
two (or more) 100%-East Asian ancestors, one great-grandparent and one
great-great-grandparent (12.5% + 6.25%=18.75%) or three
great-great-grandparents (3 x 6.25%=18.75%). For the case of my wife of
(9±2.5)% East Asian and (2±2.5)% Native American, her East-Asian
ancestor was a great-great-grandparent (or a great-great-grandparent and a
great-great-great-grandparent [6.25% + 3.125%=9.375%]) and her Native-American
ancestor was either a great-great-great-grandparent, a
great-great-great-great-grandparent, or did not exist. (The 2.5% error could
mean that the result of 2% could easily be 0%.) |
This is a
chart one can use to decide in which generation an ancestor is according to the
percentage of ancestry given by the BioGeographical Ancestry test. For example,
my (17±2.5)% East-Asian component lies closest to the
great-grandparents' percentage and my wife's (9±2.5)% East-Asian
component lies closest to the great-great-grandparents' percentage. Her
(2±2.5)% Native-American component could be either gr-gr-gr-grandparents
or gr-gr-gr-gr-grandparents or further back or none at all. |
Go back to top |
Case Studies:
http://www.ancestrybydna.com/casestudy.html. Case #1
in these studies clearly shows the effects of recombination (gene mixing) upon
reproduction: The three siblings have different admixtures of Indo-European,
Native-American and sub-Saharan-African ancestry and each one also has
different admixtures than the parents have. |
To learn how to understand the DNAPrint results see:
http://www.ancestrybydna.com/usermanual.pdf |
I have had this test done for
my wife and me, Jeanne Muriel Baril Roper. My results are given here:
Ancestry |
Estimate |
Indo-European |
83% |
East-Asian |
17% |
Native-American |
0% |
The
first contour (black line) around your BGA result delimits the space outside of
which the points are 2 times less likely, and the second contour (blue line)
delimits the space outside of which the estimates are 5 times less likely. The
third contour (yellow line) delimits the space outside of which the estimates
are 10 times less likely than your result. |
Comments of L. David Roper about these results:
This was quite a surprise to me. I expected some Native-American admixture
because of the legends of such for my great-great-great grandmother Roper;
apparently those legends are incorrect. I have no idea where the East-Asian
admixture came into my ancestry; it would have to be further back than
grandparents. Note that the confidence intervals lean toward the
Native-American side of the triangle. It may be that my East-Asian admixture is
the small minority of Native Americans that have the X mtDNA haplotype. Perhaps
the NE Asians migrated both ways, some into North America and some toward
Europe. My percentage results are the same as Brett Strobel's. |
A Genotype is the actual building block at one
location on your DNA. For instance if, at a certain location, you inherited an
'A' from your mother and a 'C' from your father, your genotype would be 'AC'
for that location. (The DNAPrint results do not distinguish paternal-maternal
order; i.e., it could be AC or CA.) There are approximately 3,000,000,000
building blocks (base pairs) in the human genome, however only 0.1% of these
building blocks are variable from person to person. The BGA test measures the
specific genotype at 70 highly informative deep ancestral locations. Genotypes
for L. David Roper:
Location: |
#958 |
#960 |
#961 |
#964 |
#966 |
#969 |
#970 |
#971 |
#972 |
#973 |
Genotype: |
GC |
CC |
GC |
GC |
CC |
CC |
CC |
CC |
CC |
TC |
Location: |
#976 |
#977 |
#978 |
#979 |
#980 |
#993 |
#1000 |
#1015 |
#1022 |
#1029 |
Genotype: |
TC |
TC |
TC |
CC |
TT |
TT |
TC |
TC |
TC |
GG |
Location: |
#1033 |
#1034 |
#1035 |
#1036 |
#1040 |
#1041 |
#1043 |
#1044 |
#1047 |
#1048 |
Genotype: |
GG |
AA |
AA |
GA |
GA |
AA |
AA |
AA |
AA |
GG |
Location: |
#1049 |
#1050 |
#1051 |
#1053 |
#1055 |
#1056 |
#1057 |
#1058 |
#1060 |
#1062 |
Genotype: |
GA |
AA |
GA |
GG |
GA |
GA |
AA |
GG |
GA |
GA |
Location: |
#1064 |
#1066 |
#1068 |
#1071 |
#1073 |
#1075 |
#1076 |
#1077 |
#1081 |
#1082 |
Genotype: |
GA |
GG |
AA |
GG |
AA |
AA |
GA |
GA |
GA |
GG |
Location: |
#1083 |
#1084 |
#1087 |
#1111 |
#1113 |
#1116 |
#1117 |
#1120 |
#1121 |
#1122 |
Genotype: |
AA |
AA |
AA |
TT |
TT |
TT |
TT |
TT |
TC |
TC |
Location: |
#1124 |
#1128 |
#1130 |
#1136 |
#1137 |
#1138 |
#1139 |
#1140 |
#1141 |
#1146 |
Genotype: |
TT |
AA |
GG |
AA |
GG |
GA |
AA |
GA |
AA |
GA |
|
Go back to
top |
|
My wife's (Jeanne Muriel
Baril Roper) are given here:
Ancestry |
Estimate |
Indo-European |
89% |
East-Asian |
9% |
Native-American |
2% |
The
first contour (black line) around your BGA result delimits the space outside of
which the points are 2 times less likely, and the second contour (blue line)
delimits the space outside of which the estimates are 5 times less likely. The
third contour (yellow line) delimits the space outside of which the estimates
are 10 times less likely than your result. |
The 2% for Native-American is well
within the measurment errors. If it is true, the responsible ancestor would
have to be further back than great-great-great grandparents if it came from one
single person in a pair. The 9% East-Asian would have to be further back than
great-grandparents if it came from one single person in a pair. Note that
the confidence intervals lean as much toward the Native-American side of the
triangle as toward the East-Asian side. This implies that the 2%
Native-American is real. |
A Genotype is the actual building
block at one location on your DNA. For instance if, at a certain location, you
inherited an 'A' from your mother and a 'C' from your father, your genotype
would be 'AC' for that location. There are approximately 3,000,000,000 building
blocks (base pairs) in the human genome, however only 0.1% of these building
blocks are variable from person to person. The BGA test measures the specific
genotype at 70 highly informative deep ancestral locations. Genotypes for
Jeanne Muriel Baril Roper:
Location: |
#958 |
#960 |
#961 |
#964 |
#966 |
#969 |
#970 |
#971 |
#972 |
#973 |
Genotype: |
GC |
GC |
GG |
CC |
GC |
TT |
CC |
TT |
CC |
TT |
Location: |
#976 |
#977 |
#978 |
#979 |
#980 |
#993 |
#1000 |
#1015 |
#1022 |
#1029 |
Genotype: |
CC |
TT |
CC |
TC |
TC |
TT |
TT |
CC |
TC |
GA |
Location: |
#1033 |
#1034 |
#1035 |
#1036 |
#1040 |
#1041 |
#1043 |
#1044 |
#1047 |
#1048 |
Genotype: |
AA |
GA |
GG |
GG |
AA |
GA |
AA |
GG |
GG |
GA |
Location: |
#1049 |
#1050 |
#1051 |
#1053 |
#1055 |
#1056 |
#1057 |
#1058 |
#1060 |
#1062 |
Genotype: |
GA |
GG |
GA |
GA |
AA |
GA |
GG |
GG |
GG |
AA |
Location: |
#1064 |
#1066 |
#1068 |
#1071 |
#1073 |
#1075 |
#1076 |
#1077 |
#1081 |
#1082 |
Genotype: |
GA |
GG |
AA |
GA |
AA |
AA |
AA |
GA |
GA |
GA |
Location: |
#1083 |
#1084 |
#1087 |
#1111 |
#1113 |
#1116 |
#1117 |
#1120 |
#1121 |
#1122 |
Genotype: |
FL |
AA |
AA |
TT |
CC |
TT |
TC |
TT |
TT |
TC |
Location: |
#1124 |
#1128 |
#1130 |
#1136 |
#1137 |
#1138 |
#1139 |
#1140 |
#1141 |
#1146 |
Genotype: |
TT |
GA |
GA |
GA |
GG |
GG |
AA |
GA |
GA |
AA |
|
|
Ancestry Limit for Gene Transfer to
Descendants There are approximately
60,000 genes in humans. The number of ancestors, if all
are unique, for which at least one gene for each are still now in one's DNA are
given by the equation: [# of ancestors in the nth
generation] = 2n= 60000, the solution is about n=16. Of
course, often an early ancestor is an ancestor more than once. In fact,
mitochondrial Eve and
Y-chromosome Adam are probably thousands of times an
ancestor of all living humans. I have done some rough calculations about how
the number of identical ancestors in a given generation might vary as one goes
back into previous generations. From those calculations I would guess that the
"ancestry limit" is about 20 generations or about 400-500 years ago. Half of
the ancestors in the generation back from that "ancestry limit" generation
cannot supply any genes to the current generation. |
Ancestry Composition tells you what percent of your DNA comes from each of 31 populations worldwide. This analysis includes DNA you received from all of your recent ancestors, on both sides of your family. The results reflect where your ancestors lived before the widespread migrations of the past few hundred years.